National Journal Club - January 2023

Topic: Treatment of Cyclopeptide Mushroom Poisoning
Presented By: VCU Program in Medical Toxicology, led by Dr. Brandon Wills.

Articles

• Mackenzie CA, et al: Cyclosporine as a novel treatment for amatoxin-containing mushroom poisoning: a case series. Toxicol Commun 2022;6:23-27.
• Tan JL, et al: Amanitin intoxication: effects of therapies on clinical outcomes – a review of 40 years of reported cases. Clin Toxicol 2022;DOI 10.1080/15563650.2022.2098139
• Mengs U, Pohl R-T, Mitchell T, Legalon SIL: The antidote of choice in patients with acute toxicity from amatoxin poisoning. Curr Pharmaceut Biotech 2012;13:1964-1970.
• Tong TC: Comparative treatment of alpha-Amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid and silybinin in a murine model. Ann Emerg Med 2007;50:282-288.

Series Moderator: Steven E. Aks, DO, FACEP, FACMT, Toxikon Consortium

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